By multiscale I mean fanned fret guitars with a 26.5" bass string and a 25.5" high E string. It seems to me the bass would sound substantially better and I heard they are comfortable and easy to get accustomed to. Here are a couple reasons to reject them. I think there isn't trem available for them. Also, there are very few pickups designed to work with them. Are there several other disadvantages too? I'm a hardtail player so maybe one of these would be good for me.