I had an "accident" while smashing an old acoustic back in the '80's courtesy of tequila shots, that rendered my right index finger numb after it had to be restitched back on to the rest of the finger (compound fracture). It had a positive effect on my marksmanship, as I couldn't feel the end of the finger so I didn't anticipate the recoil when pulling the trigger. However, it's hard to hold a pick, mostly when strumming. On electrics, I use .60mm "Star Picks" with a jagged hole in them where I can kind of feel my thumb with the tip of the index. On acoustic, I use Jim Dunlop .38 and .46mm that have very fine serrations on them for better grip. I still drop picks regularly...usually they disappear into the sound hole if I'm not using a feedback buster...but I've gotten good at pulling another out of the pick dispensers I have mounted on my acoustic/electrics, usually without losing a stroke. Dropping picks into the sound holes has got to be a "thing", since it happens so often to me. Sometimes it's hard to flip the guitar just right for them to fall out of the sound hole. Frustrating as all get out. That may have been why I smashed the guitar way back then, which deformed my finger in the first place. I've been tequila free ever since.