IMO, that's subjectively determined. Some will say yes, while others will say no. What is likely to cause at least some measurable tonal differences (again, probably just more noticeable by some) is the bridge plate material itself, with many or most of the stamped steel ones being magnetic, and some (possibly many) of the 6 (cast) saddle bridges being nonmagnetic. IME, it was mostly diminishing returns with messing with different bridges and saddles for tonal improvements only. Others will no doubt beg to differ, because we're all going to come to our own personal conclusions.