Yes but again there is the argument that on a guitar, a right handed player do the « most fine motor things » with his left hand... My personal experience is that as a right handed person, I still have more strength in my right arm. But since I started learning and playing the guitar 30 years ago, I developed more strength in my left hand and fingers than in the right. So much that when I want to open a can or something, I rather use my left hand, which is counter intuitive for many right handed persons. I see that as a result of being forced to develop my « wrong » hand, hence my conclusion that there should be really no right or wrong hand when playing an instrument. In the end, like you said I think that some right handed persons could have felt more at ease starting to learn and play on lefties guitars and vice versa. If it does not really happen is because when you are right handed, nothing encourages you to try and play a lefty guitar to begin with. But I also think that it does not really matter since you adapt quickly, because playing the guitar feels really unnatural no matter what when you’re a beginner. Edit: I have a 4 year old son and by now it is very clear that he is right handed. Each time he grabs his little guitar, he puts it indifferently one way or the other onto his leg, and at this step I am convinced he could learn both ways.