I think it's a match made in heaven. I did a gig last night with my Tele (Bootstrap Pretzel pickups)into an OD-3 and my Monoprice 15 watt. I got to open up the amp a bit and the tone was awesome. The bridge pickup especially sounded great. I've been using a Caline Orange burst and Pure Sky and they sound good too, but I think the OD-3 is the best with the Tele.