We believe they do, this is is why we use different wire in different designs. It’s not always so simple as to say one is better than the other. It’s all in the way that you use it. The difference in tone produced by PE vs Formar vs Poly has more to do with the thickness of the coating than it does the composition of color of the coating. When dealing with 42, the thickness of the copper itself is always 42. The thickness of coating on the wire varies from PE vs Poly vs Formvar. Although you can get Poly in many different sizes and Formvar and Plain Enamel may have different diameters based on the manufacturer, typically Formvar is fattest, PE is next and Poly is thinnest. The reason why the thickness of the coating of coil wire matters is because it can make your coil more or less copper-dense, along with being slimmer or fatter. A Strat pickup wound to 6.0k will sound different with different diameter of 42 because the physical properties of the pickup change based on this wire thickness. Another thing to consider is that using wire with thinner coating allows you to put more wire on the bobbin. This become important when trying to put 42 on a Tele Neck. You have a small bobbin & you’ll run out of room if you don’t use a thinner wire. This is also considered when making Higher output Strat pickups. You won’t find too many Strat Pickups using 42 formvar that read over 6.8 or so. Poly is cheapest and is easiest work with so its used in alot of cheap pickups. It gets a bad rap because of this but when applied correctly it’s every bit as useful as PE & Formvar. We use it in our Punchy Tele & Strat designs. The old Tim Shaw Gibson humbuckers used it as well as the we’ll regarded Tim White Humbucker. Then you got 42 v 43 which is another can of worms. Beyond that you’ve got magnets and various other techniques used from winder to winder. Bottom line, you have two very different Neck pickups. The one that sounds best sonically is for you to decide. You should try them both and report the sonic differences.