Interesting. So assuming you were building a larger solid pine cab for a tweed deluxe with a 15" speaker, how would the sound differ between a traditional tweed deluxe style open back cab, and a cab with a hole in the back, perhaps oval, as seen below? I assume the oval would only be effective if the speaker is centered in the cab, not offset.
When the size of the opening gets smaller relative to total volume, it becomes a semi open design AKA a ported design.
In this case the opening does not need to be centered behind the speaker, and can be on the sides of the cab.
I'm not sure if that Dumble cab falls into the ported design, but in true open back cabs there are other factors that will make the cab sound different, like baffle thickness, density, and stiffness; as well as perceived difference due to same model speakers actually sounding quite different due to age and amount of use they have had.
The proximity (and distance from walls) of two cabs being compared also strongly affects the perceived sound, and to really get a fair reading on how two different cabs sound you need to find two same model speakers that truly sound the same, and listen to the two cabs at the same angle from a great enough distance to not confuse proximity and angle.
If you've experimented with mic placement you'll have more evidence of how different a speaker can sound from different angles and locations.
When I liked V30s and had lots of them I found some V30 loaded cabs sounded a lot brighter than others, but then noticed that the brightness went with the speaker, not the cab.
If you've been playing loud electric guitar for a good number of years you may find that your left ear hears more or less treble than your right ear!
A lot of small cabs we encounter are made of very dense 3/4" MDF with rigid glued in baffles, where the materials and construction are influence the sound more than the "volume" of a cab which is open to the air and really has no effective volume at all, with regard to damping the cone vibration, or influencing and directing the sound from the back of the speaker.
The wall behind the cab has a great deal of influence on the sound!