Is a .022uf 250V cap the same thing as a Capacitor MPF RDL .022uF 250V 10% cap?

The things that matter are the capacitance value: 0.022uF (both)
And the max voltage rating : 250V (both)

In the guitar tone circuit you don't need anything near a 250V rating - 10V would still be overkill

The 10% is a tolerance, which means the individual capacitor in your hand could vary from 0.020uF to 0.024uF (roughly). 10% is typical for capacitors, and that little variation is fine (though a good ear might hear the difference from the lowest to highest value, I would put money on it).

So basically, yepp, to all intents and purposes they are equivalent.

 

si

 

Dont need a 250v. It sees millivolts. Any .022 will do.