Hi! I've been a type 2 diabetic for at least 15 years, but recently oral meds were not working, so my doc switched me to insulin. My doc went over how to inject(Humalog pen, 75/25), but he did it quickly and told me to go online for more information. I have been using the pen for 3 days, and it does not seem to be working. I upped my dose today, but my sugar is still high, and not coming down. I think I am injecting wrong. My doc told me to basically pinch an inch and inject the insulin there, between the fatty tissue and the muscle. Here is what I am doing. Roll the pen several times to distribute the insulin mix evenly(this is a mix of short and long acting insulin). Attach needle to end of pin. Dial up two units, hold the pen vertical and press the plunger to prime the pen. When I do this I don't get a stream of insulin, rather several drops that run down the needle. In order to get the pen to eject a stream I have to dial up at least 5 units, which to me is way more than what is indicated and wasteful. I have been youtubing this all morning, and the general consensus is that as long as some insulin is coming out of the tip of the needle the pen is primed properly. To inject, swab site, pinch up an inch of skin(thigh), and inject at an angle. Here is where I think I am making my mistake, and where I have questions. All the videos I see online show people pushing the syringe straight in, not at an angle, and all the way in. The needle on this pen is at least an inch and a half long. Everyone else 's on line is very short. Since this is supposed to be a subcutaneous injection, not an intramuscular one, it seems to me that if I push that needle all the way in that it's going into the muscle, not between the muscle and the skin. Those of you that use this delivery system, or who use a regular syringe, which my doctor gave me a couple of pens and a vial and needles so I can try then both and see what works best for me, I would very much appreciate your experienced input with this.