As a
"(Les Paul, superstrat, etc)," you may well be surprised what can be done with that bridge pup and both pups in series (adding a 4-way switch) and serious use of the tone control. Again, don't be
"afeared" of that there tone knob. The right Tele bridge pup, with the proper cap in the tone circuit and the tone knob down to "zero" can sound surprisingly like a humbucker!

On the other side of the coin, it'll give you some "twang" that a humbucker Les Paul can only dream of!
After 35+ years of gigging with Les Pauls exclusively, I dove head first into the Fender single coil pond a few years ago. Now, with a couple great Strats and a fantastic Tele, the Les Pauls (though I still love 'em dearly) mostly collect dust! The Strats are for "wiggle stickin'" and the Tele for almost all the rest!
Just Twangin'
Gene