I've had that problem ever since I started playing 57 years ago! In my case, my gigs are two hours max, and usually one hour (assisted living centers) since the start of Covid. My arthritic thumb on my right hand has ok days and much worse days. Fortunately, carpal tunnel that flared up in my left wrist has been dormant for a while, which I attribute to my short gigs. If I had to play a 4-hour job, I don't know if I could get through it. I'm blessed to be able to make music on my own, but there are times I would like to have the satisfaction of making music with other(s).my hands wont move where my head says to go, or at least not fast enough!