I just got a Road worn 50s tele with 7.25 inch radius, 1st time playing 7.25. I love bending, I was fretting out almost every bend, Soloing and fast playing definitely more difficult. it's playable it just feels a bit limiting, I might be able to raise the action to an annoying level, but, I've already ordered a Warmoth, 10 to 16 compound radius. for the 7.25 the Minor barre chord shape is slightly easier to grab quickly, and I noticed Thumb over low E is easier but not by much. the more modern fretboard designs seem to allow much wider range of music style and technique to be played more easily. but each musicians hand comfort and particular songs/ techniques certainly can make 7.25 a more comfortable choice... it's nice to have the choice. I think 7.25 inches is slowly fading away into the background... very few guitar manufacturers offer it for a reason. it's hard to find wooden spoked car wheels they offer less performance/flexibility, even though they were clever at one time. generally professional musicians keep a strong tally of the pros and cons of each component,, and complain or collaborate with Fender. I would like to minimize these negative attributes... I would like to maximize these positive attributes.... and so you have modern guitar neck design that offers more performance more flexibility. it can still play most of the old ways and it can play in newer ways. musicians and artists are tenacious we can force most things to work. It reminds me of track and field events where the runners wear high heels they re surprisingly fast, after they practice for a few weeks. 7.25 reminds me of high heels on the track. you can make it work but why.