But a 6V6 would feel right at home. mind you, I have about 20 6K6's so it would not bother me too much. On higher voltages they would run better in P-P circuits. For SE the bias is shifted over quite a bit even when you are running 100% dissipation. But is it doesn't sound too bad and you don't have red-plating or sparks flying then no harm done. I have had 6K6's in a 5E3 with 360V with no issues. Just a touch less loud than 6V6's and NOS 6K6GT's are still cheap.IDK if the OP is using a 5k primary/8 Ohm secondary as shown on the schematic. If he is, adding a second speaker for 16 Ohm on the 8 Ohm secondary should take care of the mismatch. Then again a tube amp has some leeway with an impedance mismatch, although that could have an audible effect. It is good to be cautious.