In the last two weeks my guitar has gone from 3 pickups, to an esquire, to a traditional 2 pickups guitar and here are my impressions. Three pickups: This is how I built the guitar and had played it that way since 2015,.. don't get me wrong the guitar sounded great but I missed that chime and overtones I kinda expected in a good single coil t style geetar. One pickup: Couple weeks ago I removed the middle and neck pickups and played the guitar on a couple gigs and around the house. I'd done this before, build one guitar as an esquire, played a gig and installed a neck pickup asap. I'm not a one pickup guy, I spend most of my time in the middle or neck position and maybe 15% of my time on the bridge pickup. With one pickup, the sustain increased and I was getting overtones that I hadn't heard on this guitar, nice. Two pickups: Yup, this is where I want to be. Lush sounds, all the tele chime and overtones i was hoping for, a fantastic sounding guitar. Why would 2 pickups be better sounding to me than 3?? Something we know about stratocasters,.. too much magnetic string pull from the larger magnetic field created by the three pickups. Now, there are always caveats. If you play in a high gain situation, you may never hear or detect a difference between 3, 2 or 1 pickups. I play into (really good) low gain tube amps and I can pick up the differences in sound. A story w/ a happy ending.