I have a lot of experience with this one. As a small handed player, I have always found a Gibson neck easier because of the scale b/w frets. However, I do love the sound of strats and teles. Warmoth makes a conversion neck which is basically a Gibson scale neck that will retrofit onto a Fender guitar. While I have small hands, I still find that I prefer a thicker profile ('59 Roundback) as I believe my hand actually fatigues less than with a thinner neck profile. I think (especially for rhythm playing) the fatter profile allows you to more easiy apply pressure to the strings with the "meat" of your hand verses a thinner profile. I have uilt two guitars with conversion necks, and both came out great. Happy hunting.