I'm not talking about what specific settings you use, but how you arrive at those settings. Here is what I do: I have two OD pedals, a Monte Allums Supra Plus modded Boss OD-3 and Monte Allums H2O Plus modded Boss BD-2. I use the OD-3 primarily with my Fender SCN equipped Strat, and the BD-2 with my GFS Fat Pat humbucker equipped parts guitar. I play through a Fender BDRI with a full JJ retube kit from Eurotubes. I like my ODs to go from a nice clean sound to a slightly overdriven sound with good pick dynamics. With the guitar volume set to about 5 or 6, I first set the pedal gain controls to zero. Then I adjust the pedal volume or level controls so that the level with the pedal on is the same or just slight greater than the level with the pedal off. Then I adjust the pedal tone control to match as closely as possible the guitar tone with the pedal on as with it off. This establishes my pedal-on "clean baseline". With all settings as described, I then start increasing the gain control so that the clean baseline just barely starts to sound a little hairy. Since increasing the gain usually increases the overall volume through the pedal, I roll the pedal volume back slightly until the pedal on/pedal off levels are the same again. From this point, as I increase the volume knob on the guitar, the OD gradually increases until it reaches the desired amount of OD with the guitar volume set to 10. Roll the guitar volume back and it cleans up nicely. It all sounds very natural. Picking dynamics are great. I can then adjust the amp volume or the pedal volume as necessary to achieve the desired overall volume without messing up the OD sound. The net results are slightly different settings on the OD-3 and BD-2 as the output levels of the two guitars are quite different. If I want more OD than either pedal provides by itself, I use the BD-2 to drive the OD-3. Sounds great. So how do you do it?