Hi m8,
OK, i'm a digital retoucher by trade, I use an A3 wacom tablet all day when I'm not playing so I'd like to think this is good advice
To answer your question, yes you can. Any wacom tablet will work proportionaly to your screen so you don't have to work at 1:1 scale.
In fact I dont because it hurts your arm after a while and Its just not practical. You didnt mention what software you'll be useing it in but I'll take it its Photoshop or illustrator or somthing similar.
Tablets take quite a while to master, its not just like picking up a pen and tracing, you have to understand exactly what the paramiters of the tablet and software do to complete a particular job + practice. I wouldnt like you to buy one and then think you've wasted your money.
My advice however is this: Get a professional to do it, it shouldnt cost you much depending on the design. Or if you can show me what you want or post a pic with a discription I'll do it for you aslong as its not a huge job.
No charge of course, I'm always happy to help somone out. you'd just have to get it printed at your end.
Unless of course you want one and want to learn how to use it. In that case go for it, there a wonderful tool.
Cheers
GS