I've got a 330/12 that I love. There's something about the Ric 12 sound that really can't be duplicated on others IMO.
That said, it's nowhere close to a "main" guitar, but it's come in handy for certain songs or certain gigs. If I had to start paring down, it would likely be one of the first to go, simply because it's more of a 'luxury/cool to have" sort of guitar.
As others have said, they take a little getting used to as they just threw 12 strings onto the same size neck as a 6.