Steve Howe from Yes was also a strat guy... though he used lots of things, I have seen him mostly on strats... (Don't look very often... )
I own a 74 Strat... it's not a ducky strat... It doesn't quack.. Mostly because of the pickups and addition electronics...
Quackless Strat
Find a strat that feels right and then experiment with the pickups and electronics until it produces a sound that you enjoy.. if not... Don't use one...