I put Red Fang's in a 35-watt Allen Accomplice, replacing Jensen Neo's -- sometimes running only one 12" and sometimes a second in an extension cabinet. I wanted a little more British sound, and I think the Red Fang's do that very well in more of a Vox'ish than Marshally way. (How's that for subjective?!) They sound great clean, with a little more mid-range and more chime in the high end, less ice-pick highs. They do compress more than the Jensen's (not necessarily a bad thing by any means), but with the additional mid-range, I believe they'll cut through tremendously well.
If you're just using the amp's own distortion and not trying to play metal, I think you'll like them a lot. [Not that there's anything wrong with metal, I just have no business advising people on what makes a "good" or a "bad" metal tone.] I doubt there's any substantial danger of blowing them.
Let us know how you like them. I did not think they needed a great amount of break-in before getting a pretty good read on their sound.