1. As stated, it will not fit. You can get a custom pickguard with a strat sized hole from warmoth for $25. I have a Duncan SSL-1 in the neck of my MIM and it sounds great.
2. Wiring was the same in my expereince.
3. My pick up covers the 5 part and you will not be disapointed. Low notes are powerful yet not wooly. The higher notes always sound smooth, but I can see the alnico two magnets making them a little more chimey and bell like.