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You never have to worry about leaving an amp on standby for an extended period of time unless there are heat buildup problems.
Heat in general should be your biggest cause for concern.
Either
1. Overheating whilst the amp is on, standby or in use...you need proper ventilation and perhaps a cooling fan if this is an issue
OR
2. Not cooling down your amp before you move it. After you finish a gig or rehearsal, you need to turn OFF the amplifier and let it cool down almost completely before moving it as sudden jarring movements can seriously reduce the life of your tubes when hot.
I hope I've been helpful,
Ward
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